1. AutoSampler 4. Solid State NMR
2. Routine 5. Minispecs & EPR
3. High Field


3. High Field

The three spectrometers in BCH 1508, 1510 and 1516 are operating at higher fields (500, 600 and 800 MHz for 1H) and are equipped with cryoprobes.

These machines can be used first if increased resolution is needed (crowded spectra, complex mixtures, overlaps, …). For example, the chemical shift separation at 800 MHz is 2 times larger than at 400 MHz.

These spectrometers are equipped with cryoprobes (helium or nitrogen cooled), allowing up to 4 fold sensitivity enhancements. These machines can thus be used with low concentration samples, for example as a last chance experiment for 13C direct measurement that do not give signal on routine machines.


The spectrometer in BCH 1516 (600 MHz) is equipped with a broadband optimized cryoprobe, delivering sensitivity enhancement for X-nuclei from 15N to 31P. The spectrometers in BCH 1508 and BCH 1510 (500 and 800 MHz) are equipped with proton-optimized triple resonance NMR ‘inverse’ TCI cryoprobes. These probes are optimized for protein samples characterization. Nevertheless, 13C direct measurements of low concentrated samples are as well possible (and recommended). The acquisition probes of these 2 machines are only tuneable to 1H and 13C. It is therefore only possible to acquire 1H and 13C direct spectra (as well as 13C and 15N indirect HSQC, HMBC, …), but no X-nuclei spectra such as 31P.

Location: BCH 1508, BCH 1510, BCH 1516

high field ________________________________________________________________________________________

5. Minispecs & EPR

Minispecs operating at 10, 20, 40 and 60 MHz (0.23, 0.47, 0.94 and 1.41 T) are available to measure the effect of contrast agent on the NMR relaxation of water or fat. T1, T2, T1rho and T2e (?) measurement techniques are implemented on these machines.

Location: CH F-0492


Detection and quantification of unpaired electrons can be done on a benchtop EPR (X band). The machine is accessible on demand (grp Emsley).

Location: BCH1504